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Figure 1 | BMC Neuroscience

Figure 1

From: Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress

Figure 1

Effect of paraquat and of differential levels of oxygen tension on the viability of primary CbG and cerebral cortical (CTX) neurons. (A) Effects of paraquat on neuronal viability. Both types of neurons were exposed to the indicated concentrations of paraquat for 24 h at 37°C. Cell viability was determined by the calcein AM and PI labeling method. Data represent the mean (± SEM) of neuronal viability from 10 experiments. The P values from Student's t-test are shown for the indicated comparisons. (B, C) Survival of neurons across days in vitro (DIV) under different levels of oxygen (5% and 20%). Viability of neurons was measured by the MTT assay. The data represent the mean (± SEM) from 3 experiments. Statistically significant differences (t-test) are shown for the indicated comparisons.

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