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Figure 5 | BMC Neuroscience

Figure 5

From: Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis

Figure 5

Generation analysis of CD8+ cells isolated from MOG-primed wt and mmp7-/- mice, using CFSE. (a, b) The proportion of IL-2-responsive progenitors that gave rise to CD8+ cells in wt mice was comparable to that observed with (d, e) MMP-7-/- mice. (c, f) MOG-responses were robust in wt, but not mmp7-/- progenitors. Percentages indicate the proportion of progenitors that surpassed the farthest generation of media-only controls (a, d).

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BMC Neuroscience

ISSN: 1471-2202

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