Table 1 Identification, cloning, and function of NBPs
Human Gene | Gene Name | Function | Interaction | Zebrafish Ortholog | mRNA Accession Number (riboprobe NTs) |
|---|---|---|---|---|---|
Arf1 | ADP-ribosylation factor 1 | Trafficking/Exocytosis | NM_201452 | NM_201452 (99–643) | |
Pi4kβ (Pik4cb) | Phosphatidylinositol 4-kinase beta | Trafficking/Exocytosis | Immuno-precipitation [29] | BM095643 | FJ032032 (1–2083) |
Vamp2 | Vesicle associated membrane protein 2/Synaptobrevin 2 | Exocytosis | Y2H | BC059626 | NM_200005 (1–894) |
Hint2 | Histidine triad protein | Mitochondrial AMP-lysine hydrolase | Y2H | CN504819 | FJ032031 (1–514) |
Slc25a25 (SCaMC2) | Ca2+-dependent mitochondrial carrier | Mitochondrial ATP-Mg/Pi carrier | Y2H | NW_001513403 | NM_213257 (65–1249) |
Pink1 | PTEN-induced kinase | Mitochondrial Kinase | Y2H | NW_001513662 | FJ032033 (1–1725) |
Trpc1 | Classical transient receptor potential-1 | Cation channel | GST-pulldown [31] | EE302043 | XM_694363.3 (1097–2334) |
Trpc5 | Classical transient receptor potential-5 | Cation channel | Immuno-precipitation and GST-pulldown [32] | AW343190 | NM_001044827 (1–2395) |
Ip3r (Itpr) | Inositol 1,4,5 trisphosphate receptor | Ca2+ release channel | Immuno-precipitation [30] | CK017406 | XM_691322 (6591–8187) |
Dan (Nbl-1) | Differential screening-selected gene aberrant in neuroblastoma | Extracellular BMP antagonist | Y2H | BC066387 | FJ032030 (1–702) |