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Table 1 Mean [cAMP]i changes observed after modulation of cAMP signalling pathway and activation of G-protein coupled glutamate and serotonin receptors

From: Imaging cytoplasmic cAMP in mouse brainstem neurons

Forskolin

1 μM

IBMX

50 μM

DDA

100 μM

Rolipram

1 μM

DHPG

100 μM

5-HT

2 μM

1.62 ± 0.12

1.45 ± 0.07

-0.12 ± 0.05

1.19 ± 0.08

0.74 ± 0.07

0.81 ± 0.05

  1. Mean data ± S. E. M. were obtained in 4 to 8 neurons in four different preparations and are presented as changes from the resting cAMP level (mean = 0.09 ± 0.03 μM). Group I metabotropic glutamate receptors (mGluR1/5) were activated with (S)-3,5-dihydroxyphenylglycine (DHPG).
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BMC Neuroscience

ISSN: 1471-2202

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