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Figure 1 | BMC Neuroscience

Figure 1

From: In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment

Figure 1

MRS voxel placement and spectrum. (A) Representative MRI featuring a frontal slice through a mouse brain with localization 1.5 mm posterior to bregma in cortex/hippocampus. Placement of the voxel of interest (VOI) sized 4.0 × 1.6 × 1.6 mm3 for spectroscopy as indicated by the white box. (B) Representative MRI featuring a frontal slice through a mouse brain with localization 0.5 mm anterior to bregma in striatum. Placement of the VOI sized 5.0 × 2.0 × 2.0 mm3 for spectroscopy as indicated by the white box. (C) Representative wild type spectra from cortex/hippocampus to show the quality of spectra received. (D) Representative wild type spectra from striatum to show the quality of spectra received.

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BMC Neuroscience

ISSN: 1471-2202

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