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Table 4 Average Cramér-Rao lower bounds (CRLB) of measured metabolites (± SD).

From: In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment

Mice type

Brain region

Gln

Glu

Tau

m-Ins

tCho

tNAA

tg

ctx/hipp

33 ± 8%

11 ± 2%

21 ± 7%

16 ± 3%

13 ± 3%

9 ± 2%

tg

str

23 ± 6%

11 ± 4%

11 ± 2%

9 ± 2%

6 ± 1%

8 ± 1%

wt

ctx/hipp

32 ± 8%

9 ± 1%

15 ± 3%

12 ± 2%

9 ± 1%

7 ± 1%

wt

str

20 ± 5%

9 ± 1%

9 ± 1%

7 ± 1%

5 ± 1%

7 ± 1%

  1. Abbreviations: Gln = Glutamine, Glu = Glutamate, Tau = Taurine, m-Ins = Myo-inositol, tCho = Choline-containing compounds, tNAA = N-acetylaspartate+N-acetylaspartylglutamate, wt = wild type mice, tg = APP/PS1 transgenic mice, ctx/hipp = parietal cortex/hippocampus, str = striatum, SD = standard deviation.