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Table 3 Brain areas with negative correlation between regional gray matter volumes and YGTSS scores in TS

From: Prefrontal and anterior cingulate cortex abnormalities in Tourette Syndrome: evidence from voxel-based morphometry and magnetization transfer imaging

Cluster size

Regions (Brodmann areas)

MNI-Space

t-value

p-value

(SVC)

  

x

y

z

  

434

Right cuneus (17)

17

-83

3

7.49

0.001

142

Left insula

-42

-39

17

6.38

0.004

728

Right precuneus (7)

15

-71

30

5.15

0.023

134

Right middle frontal gyrus (6)

38

-5

55

5.03

0.028

171

Right middle occipital gyrus (19)

29

-85

13

4.93

-

431

Left inferior frontal gyrus (11)

-23

30

-21

4.76

0.042

 

Left middle frontal gyrus (11)

-28

38

-14

4.50

0.021

 

Left superior frontal gyrus (11)

-30

46

-16

3.76

0.030

45

Right middle temporal gyrus (21)

64

-2

-16

4.62

-

33

Right superior frontal gyrus (6)

18

3

70

4.58

0.020

266

Left precuneus (7)

-9

-73

38

4.56

0.021

73

Left anterior cingulate (32)

-10

34

-6

4.51

0.020

101

Left Cuneus (19)

-27

-89

33

4.42

0.040

70

left superior parietal lobule (7)

-35

-68

43

4.26

0.033

70

Right precentral gyrus (6)

64

1

22

4.23

0.035

24

Left superior temporal gyrus (38)

-51

17

-14

4.18

-

21

Left medial frontal gyrus (10)

-11

53

18

4.16

0.039

41

Left precentral gyrus (6)

-42

-4

47

4.03

0.047

40

Right middle frontal gyrus (11)

27

29

-20

4.01

0.048

105

Right inferior frontal gyrus (11)

9

42

-18

4.00

0.050

41

Left superior occipital gyrus (19)

-38

-82

24

3.99

-

  1. MNI = Montreal Neurological Institute, SVC = small volume correction.