Experimental Group | Animal | RGCs per mm2 | Mean | S.E.M. |
---|---|---|---|---|
axotomy + vehicle injection s.c. | 1 | 360 | ||
2 | 348 | |||
3 | 594 | |||
4 | 379 | 420.6 | 58.4 | |
axotomy + vehicle injection i.o. | 1 | 443 | ||
2 | 390 | |||
3 | 378 | |||
4 | 435 | |||
5 | 365 | 402.2 | 15.5 | |
axotomy + G-CSF 20 μg/kg BW s.c. daily | 1 | 669 | ||
2 | 442 | |||
3 | 554 | |||
4 | 649 | 578.9 | 52.0 | |
axotomy + G-CSF 40 μg/kg BW s.c. daily | 1 | 729 | ||
2 | 637 | |||
3 | 778 | |||
4 | 704 | |||
5 | 773 | 742.3 | 25.8 | |
axotomy + G-CSF 40 μg/kg BW s.c. daily (start 1 d before surgery) | 1 | 641 | ||
2 | 876 | |||
3 | 696 | |||
4 | 872 | 771.3 | 60.3 | |
axotomy + G-CSF 500 ng i.o. on days 0, 4, 7 and 10 after axotomy | 1 | 638 | ||
2 | 613 | |||
3 | 773 | |||
4 | 703 | 681.8 | 35.8 |