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Figure 6 | BMC Neuroscience

Figure 6

From: Evidence for oxidative stress in the developing cerebellum of the rat after chronic mild carbon monoxide exposure (0.0025% in air)

Figure 6

PV, GAD, CB and Syn-1-IR in the cerebellar cortex of CO exposed and control rat pups. Fig. (a), (a1), (a2) and (a3), PV IR in groups A, B, C, and D respectively shows PV-IR (in green color) in neuronal bodies and processes in the M, P, and G layers. PV-IR in all 3 CO-groups was not different when compared to group D. Fig. (b), (b1), (b2) and (b3), GAD-IR in groups A, B, C, and D respectively shows GAD-IR (green color) in neuronal bodies, processes and button terminals in the M, P, and G layers. GAD-IR in all 3 CO-groups was decreased when compared to the control, group D. Fig. (c), (c1), (c2) and (c3), shows CB-IR in groups A, B, C, and D respectively. CB-IR (green color) is localized mainly in PCs and their processes. Fig. (d), (d1), (d2) and (d3), shows Syn-1-IR (red dots) in groups A, B, C, and D. Syn-1-IR is localized in button terminals respectively of the 3 layers. There was a pronounced decrease in Syn-1-IR in group A and B and to a lesser extent (but not significant) in group C. Scale bar is 150 um in Figs. a-a3, and b-b3, and 200 um in figs c-c3 and d-d3.

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