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Figure 3 | BMC Neuroscience

Figure 3

From: Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans

Figure 3

Serotonin-controlled learning behavioral. A. Schematic diagram of Slowing Responses in C. elegans. The basal and enhanced slowing responses (BSR), which are mediated by dopamine and serotonin, respectively are used to associate previous feeding experience. For the basal slowing response worms are well fed up until they are assayed. For the enhanced slowing response (ESR), there is a 30 min starvation period before they are assayed. (B) Basal (BSR) and enhanced (ESR) slowing responses in wild type animals fed with control or bilobalide (BB). (C) BSR and ESR in the mod-1 mutant worms fed with vehicle control or treated with BB. (D) BSR and ESR in the cat-2 mutant worms control or treated with BB. Four separate trials were performed for each strain. Error Bars represent the standard error; asterisk; p < 0.05, Student's t test. (E) BSR and ESR in the ser-4 mutant worms fed with vehicle control or with BB.

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