Configuration-specific facilitation phenomena explained by layer 2/3 summation pools in V1
© Çürüklü and Lansner; licensee BioMed Central Ltd. 2009
Published: 13 July 2009
Our laminar model of the layers 4 and 2/3 of V1 addresses development of the horizontal connections found in these two cortical layers as well as configuration-specific facilitation phenomena . We assumed that in both these cortical layers synapse strengths are subject to change due to visual experience. In the model, poorly tuned LGN input targets solely layer 4, whereas layer 2/3 receives sensory input from layer 4. Based on these assumptions, the model demonstrates how correlation based networks of horizontal connections are developed simultaneously in both these layers. Rapid improvement of orientation selectivity (OS) during the first weeks after eye opening, when the eyes are subject to normal visual experience has been reported earlier in several species [2, 3]. Note that this critical period coincides with the development of the horizontal connections .
- Polat U, Norcia AM: Elongated physiological summation pools in the human visual cortex. Vision Res. 1998, 38: 3735-3741. 10.1016/S0042-6989(97)00426-4.PubMedView ArticleGoogle Scholar
- Hubel DH, Wiesel TN: Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. J Physiol. 1962, 160: 106-154.PubMed CentralPubMedView ArticleGoogle Scholar
- White LE, Coppola DM, Fitzpatrick D: The contribution of sensory experience to the maturation of orientation selectivity in ferret visual cortex. Nature. 2001, 411: 1049-1052. 10.1038/35082568.PubMedView ArticleGoogle Scholar
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