Figure 1

(a) Schematic diagram demonstrating the effect of perturbation received by a spiking neuron at time t. The cycle containing the perturbation defines the first order STRC and the subsequent cycles define the higher order STRC terms. (b) The STRC's computed for neuron receiving perturbation through a GABA_A mediated synapse at hyperpolarizing reversal potential of E _R = -80 mV. (c) The STRC's computed for neuron receiving perturbation through a GABA_A mediated synapse at shunting reversal potential of E _R = -55 mV. The resting membrane potential of neuron is -65 mV. The synaptic parameters are t _R = 0.1 ms, t _D = 8 ms, g _s = 0.15 mS/cm². The intrinsic period of firing for the neuron was T₀ = 31 ms.