From: Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease
WT | R6/2 | |
---|---|---|
Proliferation in the SVZ | ||
PCNA (×103) | 7.42 ± 3.11 | 8.49 ± 2.16 |
Neurogenesis in the OB granular cell layer | ||
BrdU (×103) | 69. 9 ± 15.1 | 46.8 ± 11.3 # |
% BrdU/NeuN | 88 ± 4 | 87 ± 3 |
BrdU × % BrdU/NeuN (×103) | 61.5 ± 15.1 | 40.7 ± 11.2 # |
Neurogenesis in the OB glomerular layer | ||
BrdU (×103) | 10.1 ± 3.9 | 4.8 ± 1.7 # |
% BrdU/NeuN | 90 ± 3 | 90 ± 6 |
BrdU × % BrdU/NeuN (×103) | 9.1 ± 3.5 | 4.4 ± 1.7 # |
% BrdU/TH | 8 ± 2 | 14 ± 3 # |
BrdU × % BrdU/TH | 775 ± 301 | 656 ± 270 |