The effect of mesenchymal stem cell transplantation on the recovery of bladder and hindlimb function after spinal cord contusion in rats

Table 1 Urodynamic Study and Bladder Volume of Experimental and Control Groups at 28 and 56 Days after Transplantation.

	PTD28			PTD56			p-value
	PBS (n = 7)	hFb (n = 11)	hMSC (n = 9)	PBS (n = 7)	hFb (n = 9)	hMSC (n = 6)
Voiding frequency (time/min)	0.80 ± 0.09	0.82 ± 0.16	0.76 ± 0.32	0.79 ± 0.11	0.82 ± 0.19	0.92 ± 0.07	>0.05*
Maximal pressure (cmH₂O)	9.21 ± 5.30	9.60 ± 4.2	9.70 ± 4.11	9.00 ± 5.77	8.11 ± 7.39	10.33 ± 4.50	>0.05*
Pattern of regularity (%)†	43	45	44	43	22	50	>0.05*
Detrusor contraction without voiding (%)†	43	36	44	43	44	50	>0.05*
Gross pattern of voiding (%)†							>0.05*
Flaccid	29	27	13	29	33	17
Hyperreflexia	71	73	87	71	67	83
Normal	0	0	0	0	0	0
Bladder volume (mm*)	1345.25 ± 1206.27	1263.75 ± 838.05	1279.57 ± 1310.69	1874.47 ± 1452.13	1925.99 ± 1591.44	1594.45 ± 703.36	>0.05*

PTD: post-transplantation day, PBS: control group received phosphate-buffered saline, hFb: control group received human fibroblast, hMSC: experimental group received human mesenchymal stem cell * by one-way AVOVA, ** by Fisher's exact test, † No. of detectable cases (%)

ISSN: 1471-2202