Representative images of microglia in the TRN following nerve implantation into the thalamus. (a and b) are deconvolved digital images, (c) is a non-deconvolved image and (d) is a confocal image. The neurons which regenerated axons into the grafts were retrogradely labelled with fluorogold (a, b and c) or CTB (d). There is clearly increased CD11b activity in the TRN around the retrogradely - labelled neurons which are regenerating axons (b) compared with the contralateral (uninjured) side (a). There was close contract between microglia and TRN neurons with regenerating axons (arrows in c and d). The scale bar in (a) also applies to (b).