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Figure 4 | BMC Neuroscience

Figure 4

From: Long descending cervical propriospinal neurons differ from thoracic propriospinal neurons in response to low thoracic spinal injury

Figure 4

Comparative post-injury response. The expression profiles illustrate the normalized -ΔΔCp expression values of the post-injury response for both the TPS and LDPT neurons at the same survival times as in Figure 1 and numbered 1-4, with low expression values being represented by green and high expression in red. Significant changes in expression were determined using a 2-factor ANOVA, and then cluster analysis to reveal patterns in the expression profiles. As illustrated in this heat map, the differences in the post-injury response are striking. While many of the genes in LDPT neurons are down-regulated following a T9 level axotomy, the opposite is found in TPS neurons were there is a strong up-regulation following axotomy. The data illustrated in this heat map clearly demonstrate a differential response to a T9 level axotomy.

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