Figure 5
TTX antagonizes ATX-induced sodium influx in cells expressing rNa v 1.2, rNa v 1.4 and rNa v 1.5 α-subunits. Time-response for TTX antagonism of ATX-induced sodium influx in cells expressing rNav1.2 (a), rNav1.4 (b) and rNav1.5 (c) α-subunits; (d) Concentration-response for TTX antagonism of ATX-induced sodium influx in cells expressing rNav1.2, rNav1.4 and rNav1.5 α-subunits. Each data point represents the mean ± SEM from two different cultures performed in triplicate.