Figure 5
From: Sperry versus Hebb: Topographic mapping in Isl2/EphA3 mutant mice
The total amount of EphA receptor on the RGCs across the retina is composed of EphA3, EphA5 and EphA6 (EphA3/5/6). The separation between two sets of axons [EphA3+ (blue) and EphA3- (cyan)] is smaller if they originate from temporal retina. Because the gradient of the endogenous EphA receptor is maximal in the temporal retina EphA3- axons in this region have the smallest distance to the EphA3+ axons with similar overall levels of the receptor (dashed lines).