Figure 4
From: Apolipoprotein-E forms dimers in human frontal cortex and hippocampus
ApoE dimers are absent in the AD apoE4/4 brain homogenates. The absence of apoE dimers in AD apoe4/4 brains was confirmed in all available samples (n = 7) and compared to a reference AD apoE3/3 brain. Samples were analysed under non-reduced (NR) and reduced (R) conditions and western blotting was performed using goat anti-apoE polyclonal antibody. The human brain samples (AD n = 8) are identified according to the Case # code given in Table 1.