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Figure 6 | BMC Neuroscience

Figure 6

From: Dynamics of peptidergic secretory granule transport are regulated by neuronal stimulation

Figure 6

Secretagogues differentially affect instantaneous velocity and direction. Instantaneous velocity and direction were calculated for tracked LDCVs in neurons kept under basal conditions or exposed to PMA or KCl for 5 min. LDCVs moving in the retrograde direction were assigned a negative sign, and those moving in the anterograde direction received a positive sign (A); the distribution of binned data is shown for representative cells from each treatment group. The fraction of LDCVs stopped or moving in a given direction (B) is plotted as an average; the relationship between direction and velocity was also analyzed (C). One-way ANOVA with Bonferroni post-test (SPSS package): *, p < 0.02; **, p < 0.01.

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