Figure 1From: Different methods for administering 17β-estradiol to ovariectomized rats result in opposite effects on ischemic brain damageStudy flow-chart. All animals were ovariectomized day 0 of the experiment, and at the same time Gr.P/P and Gr.P/E received placebo implants, while Gr.E/E and Gr.E/P received estrogen implants. Day 14 of the experiment, all animals underwent 60 minutes of MCAo. During the anesthesia, blood samples were drawn and the implants were replaced with new ones. Gr.P/P and Gr.E/P received placebo implants, while Gr.E/E and Gr.P/E received estrogen implants. On day 17 of the experiment, all animals were sacrificed, trunk blood collected and brains harvested for analysis.Back to article page