Intrinsic response of thoracic propriospinal neurons to axotomy

BMC Neuroscience

Table 4 Specific Regeneration Associated and Neuroprotective Genes of Interest Exhibiting Significant Change in Expression Post-Injury

Gene Name	Symbol(s)	Reference
Actin, beta	Actb	[76]
Adenylate cyclase activating polypeptide 1	Adcyap1, Pacap	[77, 78]
Activating transcription factor 3	Atf3	[8, 79–82]
CD44 Molecule	Cd44	[23]
cAMP response element modulation	Crem, Icer	[83]
Cathepsin B	Ctsb	[84]
Growth arrest and DNA-damage-inducible 45 alpha	Gadd45a	[85]
Growth-associated protein 43	Gap43	[8, 86–88]
Heat shock 27 kDa protein	Hspb1	[79, 82, 89–91]
SRY-related HMG-box gene 11	Jun	[8, 23, 92, 93]
Jun oncogene	Sox11	[83, 94]
Signal transducer and activator of transcription 3	Stat3	[23, 93]
Translocator protein (18 kDa)	Tspo, Bzrp	[95, 96]
Tubulin, beta 3	Tubb3, Tuj1	[97]

Specific genes from our complied lists of genes of interest (GOI) that demonstrated a significant (p = 0.01) change in expression following T9 axotomy, as determined by a 2-factor ANOVA. 3.1 , Genes known to be associated with axonal regeneration, cell survival and neuroprotection. These gene lists are arraigned in alphabetical order and include both the symbol and full gene name. Also included in this table are a series of references used to classify these genes into their specific category.

ISSN: 1471-2202