Figure 3
From: Newly generated cells are increased in hippocampus of adult mice lacking a serine protease inhibitor
Increase of Gli1 and Ptc1 and decrease of Gli3 expression in PN-1 -/- mice. (A) In situ hybridization of Ptc1, Gli1 and Gli3 in WT and PN-1 -/- mice without (CTR) and with 12 days of running wheel exercise (RUN). (B) Quantification of the in situ hybridization of Ptc1, Gli1 and Gli3 in WT and PN-1 -/- mice without and with 12 days of running wheel exercise (C) Changes in Ptc1, Gli1, and Gli3 expression detected by RT-PCR in wild type and mutant mice without and with running exercise. All data are the means of 3 animals/condition/genotype. *P < 0.05, **P < 0.01; ***P < 0.001. Scale bar: A 100 μm.