Figure 5

Axonal transport to spinal cord neurons (longitudinal). (a-c) Magnified, back illuminated view of an individual motor neuron in an oblique longitudinal section through a portion of the ventral horn of the spinal cord (Macaca fascicularis), and seen at lower magnification in figures (b) and (c). The dark orange material seen inside the cell and filling the cell body and dendritic processes is the product of a chemical reaction carried out by an administered enzyme, horseradish peroxidase. To introduce this exogenous enzyme into the cell, it was conjugated to WGA, an ATF (axonal transport facilitator), then injected into a muscle innervated by the axons which arise from these neuron cell bodies. Scale bars (a) = 50 μm, (b) = 200 μm, (c) = 400 μm.