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Table 1 Genomic locations of Kv3 family orthologs in zebrafish genome (Zv8)

From: Functional effects of spinocerebellar ataxia type 13 mutations are conserved in zebrafish Kv3.3 channels

Chromosome

Identity 1

Strand

N-term. Exon 2

S1-S6 Exon 2

Prox. C-term. Exon 2

Distal C Exon 2

Alt. C Exon 2

7

kcnc1a

+

33,357,526

33,399,062

33,413,557

33,416,890

33,417,909

25

kcnc1b

-

4,398,437

4,372,686

4,369,562

4,367,934

 

43

kcnc2

-

2,653,160

2,619,906

2,617,395

2,614,222

 

3

kcnc3a

+

29,217,143

29,277,151

29,286,001

29,288,301

29,305,269

24

kcnc3b

-

35,119,437 4

35,441,453

35,436,978

35,394,285(+)5

 

8

kcnc4

-

25,733,068

25,708,221

25,706,162

25,696,460

 
  1. 1 Identities were assigned on the basis of the phylogenetic and syntenic analyses shown in Figs. 1-3.
  2. 2 The identified exons encode the N-terminus, the S1-S6 membrane domain, the proximal portion of the C-terminus, and one or more putative sequences for the distal C-terminus, which may be alternatively spliced. The numbers correspond to the chromosomal positions of each exon.
  3. 3 According to Zv8, there is an additional exon encoding a Kv3 N-terminus on chromosome 4 (minus strand) at position 2,762,001. Because previous genome releases contained stray Kv3 exons that disappeared in subsequent releases, this exon is likely to reflect an assembly error (data not shown).
  4. 4 In Zv8, the N-terminal exon of kcnc3b (italics) is out of order compared to the other exons.
  5. 5 In Zv8, the distal C-terminal exon of kcnc3b has been mapped to the plus strand, in contrast to the other exons.