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Figure 7 | BMC Neuroscience

Figure 7

From: Inhibition of cerebrovascular raf activation attenuates cerebral blood flow and prevents upregulation of contractile receptors after subarachnoid hemorrhage

Figure 7

Sections from the basilar artery showing ET B , 5-HT 1B and AT 1 immunoreactivity in the smooth muscle cell layer. a) ETB; sham, b) ETB; SAH, c) ETB; SAH treated with SB386023-b after 6 h, d) ETB; SAH treated with SB386023-b after 12 h, e) 5-HT1B; sham, f) 5-HT1B; SAH, g) 5-HT1B; SAH treated with SB386023-b after 6 h, h) 5-HT1B; SAH treated with SB386023-b after 12 h, i) AT1; sham, j) AT1; SAH, k) AT1; SAH treated with SB386023-b after 6 h, l) AT1; SAH treated with SB386023-b after 12 h. There are increased expressions of the ETB, 5-HT1B and AT1 receptor protein levels in the SAH compared to the sham operated rats. Treatment with SB386023-b after 6 h prevented the increased protein expression in the smooth muscle cells. Data were obtained with confocal microscopy.

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BMC Neuroscience

ISSN: 1471-2202

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