Genes Upregulated compared to vehicle control | |||
---|---|---|---|
Gene Symbol | Name | SAHA | NaB |
Ctnnb1 | Catenin, beta-1 | 1.31 ± 0.02 | 1.82 ± 0.34 |
Gli1 | glioma-associated oncogene | 5.26 ± 1.90 | 4.19 ± 2.77 |
Neurod1 | Neurogenic differentiation1 | 4.28 ± 1.78 | 1.45 ± 0.60 |
Neurog1 | Neurogenin 1 | 9.86 ± 4.35 | 2.79 ± 1.38 |
Tcf4 | Transcription factor 4 | 1.50 ± 0.34 | 1.09 ± 0.18 |
p21 (Cdkn1a) | Cyclin-dependant kinase inhibitor 1a | 5.48 ± 2.98 | 3.35 ± 0.99 |
p27 (Cdkn1b) | Cyclin-dependant kinase inhibitor 1b | 2.70 ± 0.64 | 2.34 ± 0.31 |
p57 (Cdkn1c) | Cyclin-dependant kinase inhibitor 1c | 1.89 ± 0.48 | 3.33 ± 1.17 |
Shh | Sonic hedgehog | 41.57 ± 6.98 | 6.31 ± 2.37 |
Genes Downregulated compared to vehicle control | |||
Gene Symbol | Name | SAHA | NaB |
Ascl1 | Achaete-scute complex homolog 1 | -2.36 ± 0.71 | -3.43 ± 0.92 |
Cdk2 | Cyclin-dependant kinase 2 | -4.64 ± 1.91 | -8.37 ± 5.87 |
Cdk4 | Cyclin-dependant kinase 4 | -3.35 ± 0.70 | -4.18 ± 0.17 |
Ccnd1 | Cyclin D1 | -1.55 ± 0.63 | -1.87 ± 0.17 |
Hes1 | Hairy/enhancer of split, Drosophila homolog of, 1 | -3.89 ± 1.90 | -5.56 ± 0.57 |
Hes5 | Hairy/enhancer of split, Drosophila homolog of, 1 | -11.87 ± 1.18 | -23.85 ± 3.15 |
c-Myc | V-myc avian myelocytomatosis viral oncogene homolog | -1.92 ± 0.77 | -2.44 ± 1.05 |
Olig2 | Oligodendrocyte lineage transcription factor 2 | -1.06 ± 0.03 | -2.83 ± 1.71 |
Pax6 | Paired box gene 6 | -2.04 ± 1.18 | -4.22 ± 1.92 |
Sox1 | SRY-box 1 | -4.46 ± 3.33 | -4.96 ± 2.52 |
Sox2 | SRY-box 2 | -3.08 ± 1.60 | -3.44 ± 1.06 |
Sox9 | SRY-box 9 | -2.35 ± 0.25 | -1.24 ± 1.06 |