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Table 2 Number and diameter of myelinated axons, thickness of their myelin sheaths and score of behavioral test

From: Ciliary neurotrophic factor promotes motor reinnervation of the musculocutaneous nerve in an experimental model of end-to-side neurorrhaphy

MCN

Number of myelinated axons (n ± SD)

Axonal diameter (μm ± SD)

Myelin sheath thickness (μm ± SD)

BT ± SD

intact

1259 ± 98

4.08 ± 2.11

1.37 ± 0.64

5.00 ± 0.00

PBS

1473 ± 135‡

1.79 ± 0.03‡

0.61 ± 0.01‡

3.53 ± 0.52‡

Cerebrolysin

1282 ± 124#

2.16 ± 0.03+‡

0.81 ± 0.01+‡#

4.08 ± 0.49‡

CNTF

782 ± 78+‡

2.11 ± 0.03+‡

0.79 ± 0.01+‡

5.00 ± 0.00+

  1. Mean numbers of myelinated axons, their diameters and thickness of myelin sheaths in intact MCN and in MCN stumps after end-to-side anastomosis in phosphate buffered saline (PBS-), Cerebrolysin- and CNTF-treated rats as well as their mean scores for behavioral test (BT).
  2. ‡ indicates statistical significance (P < 0.05) when comparing rats of experimental groups with intact rats; + indicates statistical significance (P < 0.05) when comparing rats with ALZET minipumps filled with CNTF or Cerebrolysin and PBS; # indicates statistical significance (P < 0.05) when comparing rats with ALZET minipumps filled with Cerebrolysin and CNTF.