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Table 1 Genetic interactors of Dys and Dg in muscle have photoreceptor axon pathfinding defects and shortened rhabdomeres

From: New Dystrophin/Dystroglycan interactors control neuron behavior in Drosophila eye

Genotype

Defective lamina plexuses (%)

n, analyzed optic lobes

χ2-value

Relative rhabdomere length

n, analyzed eyes

p-value

OregonR (Control)

4.9

41

 

1.0 ± 0.12

8

-

CG34400[c05107]

35.3

17

21.7 ***

-

-

-

chif[BG02820]

46.7

15

28.4 ***

-

-

-

Fhos[A055]

4.3

23

3.3 × 10-2

-

-

-

Grh[IM]

11.8

17

2.1

-

-

-

nAcRα-30D[EY13897]

5.0

40

6.5 × 10-2

-

-

-

Nrk[k14301] 1

28.6

14

15.5 ***

-

-

-

SP2353[MB00605]

12.5

32

2.6

-

-

-

eyeFlpFRT/Lis1FRT

-

-

-

0.94 ± 0.08

10

0.20

GMR-Gal4/+

8.0

25

-

1.00 ± 0.06

32

-

Cam RNAi /GMR-Gal4

22.2

18

5.8*

0.71 ± 0.03

6

1.3 × 10 -12 ***

2 capt RNAi /GMR-Gal4

36.6

71

17.1 ***

0.81 ± 0.03

18

2.9 × 10 -11 ***

3 capt RNAi /GMR-Gal4

42.9

49

22.6***

0.76 ± 0.07

18

1.0 × 10 -14 ***

CG7845 RNAi /GMR-Gal4

0.0

13

6.1

-

-

-

Fkbp13 RNAi /GMR-Gal4

4.7

21

6.1

-

-

-

Lis1 RNAi /GMR-Gal4

40.6

32

20.5 ***

0.72 ± 0.07

18

1.8 × 10 -11 ***

mbl RNAi /GMR-Gal4

18.2

22

3.2

0.85 ± 0.06

10

1.4 × 10 -7 ***

POSH RNAi /GMR-Gal4

13.3

15

0.9

-

-

-

Rack1 RNAi /GMR-Gal4

7.1

14

6.6 × 10-4

0.94 ± 0.06

11

0.13

robo RNAi /GMR-Gal4

25.0

20

7.8 **

0.92 ± 0.04

6

0.14

SP2353 RNAi /GMR-Gal4

16.7

12

2.4

0.94 ± 0.05

 

0.014*

Nrk RNAi /GMR-Gal4

-

-

-

0.82 ± 0.05

14

3.8 × 10 -11 ***

CG34400 RNAi /GMR-Gal4

-

-

-

0.81 ± 0.05

17

2.0 × 10 -9 ***

Grh RNAi /GMR-Gal4

-

-

-

0.86 ± 0.04

6

1.1 × 10 -4 ***

vimar RNAi /GMR-Gal4

9.5

21

1.0

0.76 ± 0.05

13

2.2 × 10 -15 ***

Pgk RNAi /GMR-Gal4

-

-

-

0.77 ± 0.04

18

4.2 × 10 -6 ***

  1. all mutant alleles were obtained from BDSC, all RNAi mutants - from VDRC, 1 - from DGRC
  2. 2 Vienna stock number v21995
  3. 3 Vienna stock number v101588