From: Longitudinal diffusion tensor imaging in amyotrophic lateral sclerosis
 | Side | Cluster size | x | y | z | T | p |
---|---|---|---|---|---|---|---|
T0 FA correlation with ALSFRS-R | Â | Â | Â | Â | Â | Â | Â |
Right Brainstem, Midbrain | r | 233 | 10 | -24 | -21 | 4.41 | 0.019* |
Cerebellum, Posterior Lobe, Declive | r | 251 | 13 | -58 | -19 | 3.99 | 0.04* |
T0 FA correlation with disease duration | Â | Â | Â | Â | Â | Â | Â |
Precentral Gyrus, WM, below BA 6 | r | 596 | 4 | -27 | 70 | 4.93 | 0.007* |
Precentral Gyrus, subgyral, WM, Corona radiata | r | Â | 6 | -30 | 61 | 4.52 | 0.014* |
Sub-lobar, WM, CST, Internal capsule | l | 867 | -31 | -26 | 17 | 4.58 | 0.013* |
Sub-lobar, WM, CST, Internal capsule | l | Â | -30 | -18 | 15 | 4.47 | 0.017* |
Cerebellum, Anterior Lobe, Culmen | r | 317 | 12 | -56 | -15 | 4.56 | 0.014* |
Sub-lobar, WM, CST, Corona radiata | l | 202 | -13 | -29 | 51 | 4.37 | 0.02* |
T0 FA correlation with SF36 | Â | Â | Â | Â | Â | Â | Â |
Cerebellum, Anterior Lobe, Culmen | r | 715 | 19 | -43 | -27 | 5.24 | 0.004* |
Cerebellum, Anterior Lobe | r | Â | 10 | -42 | -33 | 4.4 | 0.019* |
Cerebellum, Anterior Lobe | l | 561 | -10 | -41 | -33 | 4.84 | 0.008* |
Cerebellum, Anterior Lobe, Culmen | l | Â | -16 | -42 | -27 | 4.22 | 0.027* |
Follow-up FA correlation with ALSFRS-R | Â | Â | Â | Â | Â | Â | Â |
Precentral Gyrus, subgyral, WM, BA 6 | r | 469 | 50 | 2 | 38 | 6.35 | 0.006* |
Precentral Gyrus, subgyral, WM, BA 6 | r | Â | 46 | -5 | 46 | 6.11 | 0.008* |
Frontal Lobe, Middle Frontal Gyrus, WM | r | 233 | 33 | 13 | 50 | 5.99 | 0.01* |
Precentral Gyrus, WM, Corona radiata | r | 417 | 29 | -15 | 56 | 5.87 | 0.011* |
Precentral Gyrus, WM, Corona radiata | l | 219 | -16 | -12 | 59 | 5.01 | 0.014* |
Follow-up FA correlation with disease duration | Â | Â | Â | Â | Â | Â | Â |
Capsula Inerna, Crus post., CST | l | 1722 | -24 | -19 | 2 | 6.87 | 0.003* |
Sub-lobar, WM, Capsula Inerna, Crus post., CST | l | Â | -28 | -25 | 14 | 5.7 | Â |
Internal capsule, Crus post., CST | r | 408 | 24 | -16 | -4 | 5.69 | 0.014* |
Internal capsule, Crus post., CST | r | Â | 32 | -17 | -5 | 4.12 | Â |
External capsule | r | 431 | 31 | -12 | 10 | 5.61 | 0.015* |
Follow-up FA correlation with SF36 | Â | Â | Â | Â | Â | Â | Â |
Brainstem, Pons, CST | l | 387 | -11 | -32 | -34 | 5.37 | 0.02* |