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Figure 1 | BMC Neuroscience

Figure 1

From: Distinct muscarinic acetylcholine receptor subtypes mediate pre- and postsynaptic effects in rat neocortex

Figure 1

CCh and linopirdine effects on neuronal AP firing. A, B. Voltage traces of a neocortical neurone in control condition (A) and in the presence of 10 μM CCh (B). The traces show voltage responses to current injections of 0.40 and 0.50 nA (durations 600 ms). Note the increased number of APs in the presence of 10 μM CCh compared to control condition. C, D. Plot of the average number of APs vs. current injection in control conditions and in the presence of 10 μM CCh (C; n = 40) or 10 μM linopirdine (D, n = 12). These experiments were performed in STRC. *: p < 0.05 vs. control, ***: p < 0.001 vs. control

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