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Table 1 Top 25 highly-expressed genes in AMC based on fold change. Both MATLAB and GeneSpring analysis are represented

From: Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain

 

Genes from MATLAB analysis

 

Genes from Genespring analysis

Gene Symbol

Gene Title

Fold Change

Function

Gene Symbol

Gene Title

Fold Change

Function

Sla

Src-like adaptor

73.34

protein binding

LRRGT00193

Unknown

574.79

Unknown

Dpysl3

dihydropyrimidinase-like 3

31.01

nervous system development

Rnf152

ring finger protein 152

35.04

Unknown

Sox4

SRY (sex determining region Y)-box 4

28.33

pro-B cell differentiation

Syncrip

Synaptotagmin binding, cytoplasmic RNA interacting protein

26.62

mRNA processing

Rprm

reprimo, TP53 dependent G2 arrest mediator candidate

19.13

cell cycle arrest

Chst8

carbohydrate (N- acetylgalactosamine 4–0) sulfotransferase 8

26.17

sulfur metabolic process

Satb2

SATB homeobox 2

18.05

negative regulation of transcription

Rpl28

ribosomal protein L28

19.32

translation

Dcx

Doublecortin

16.64

neuronmigration

Slc16a7

solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

18.85

transport

Crmp1

collapsin response mediator protein 1

15.50

neuron development

Crmp1

collapsin response mediator protein 1

18.54

neuron development

Syt16

synaptotagmin XVI

13.53

protein binding

LOC100158225

hypothetical protein LOC100158225

17.44

Unknown

Cct8

chaperonin containing Tcp1, subunit 8 (theta)

13.53

protein folding

Bmp2

bone morphogenetic protein 2

16.43

ossification

RGD1310352

similar to HTGN29 protein; keratinocytes associated transmembrane protein 2

13.42

Unknown

Dcx

doublecortin

15.26

neuron migration

Appbp2

amyloid beta precursor protein (cytoplasmic tail) binding protein 2

13.28

Transport

Mab21l1

mab-21-like 1 (C. elegans)

14.54

positive regulation of cell proliferation

Cxcr4

chemokine (C-X-C motif) receptor 4

12.76

ameboidal cell migration

Hmgb3

high mobility group box 3

14.14

negative regulation of myeloid cell differentiation

Ect2

epithelial cell transforming sequence 2 oncogene

12.50

cell morphogenesis

Baz1a

bromodomain adjacent to zinc finger domain, 1A

13.89

protein binding

Hmgb3

high mobility group box 3

12.47

negative regulation ofB cell differentiation

Sox4

SRY (sex determining region Y)-box 4

13.43

pro-B cell differentiation

Hs3st5

heparan sulfate (glucosamine) 3-O-sulfotransferase 5

12.32

protein amino acid sulfation

LOC688455

hypothetical protein LOC688455

12.93

Unknown

Cfl2

cofilin 2, muscle

12.21

protein binding

Cxcr4

chemokine (C-X-C motif) receptor 4

12.92

ameboidal cell migration

Tnc

Tenascin C

11.93

negative regulation of cell adhesion

Spint2

serine peptidase inhibitor, Kunitz type, 2

12.49

serine-type endopeptidase inhibitor activity

Nap1l3

nucleosome assembly protein 1-like 3

10.88

nucleosome assembly

Zfml

zinc finger, matrin-like

12.20

nucleic acid binding

Mex3b

mex3 homolog B (C. elegans)

10.78

RNA binding

Nradd

neurotrophin receptor associated death domain

11.65

signal transduction

Smarca1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

10.72

brain development

Bcl7c

B-cell CLL/lymphoma 7 C

11.44

Unknown

Sh3bgrl

SH3 domain binding glutamic acid-rich protein like

9.74

Unknown

Tmeff1

transmembrane protein with EGF-like and two follistatin-like domains 1

11.43

multicellular organismal development

Ascc3l1

Activating signal cointegrator 1 complex subunit 3-like 1

9.58

RNA splicing

Mtus1

mitochondrial tumor suppressor 1

11.12

cell cycle

Bex4

brain expressed gene 4

9.50

Nucleus

Adfp

Adipose differentiation related protein

10.85

response to organic cyclic substance

Fam164a

family with sequence similarity 164, member A

9.49

Unknown

Ttk

Ttk protein kinase

10.65

protein amino acid fig7 phosphorylation

LOC294446

similar to Myristoylated alanine-rich C-kinase substrate (MARCKS) (ACAMP-81)

9.44

calmodulin binding

Lrrc20

leucine rich repeat containing 20

10.63

protein binding