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Figure 3 | BMC Neuroscience

Figure 3

From: New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: preclinical and clinical applications in Alzheimer’s disease

Figure 3

Linearity of the CSF sAPPα assays. A: Human sAPPα assay. Serial dilutions of h-CSF between 1/2.5 and 1/20 were assayed and compared to serial dilutions of recombinant h-sAPPα at concentrations between 0 ng/ml and 200 ng/ml. Results were calculated from the 665 nm/620 nm ratios and expressed in delta F. Slope for h-CSF: 1.35 ± 0.04; slope for recombinant h-sAPPα: 1.45 ± 0.05. B: Rodent sAPPα assay. Serial dilutions of r-CSF from 1/2.5 to 1/10 were assayed and compared to serial dilutions of recombinant r-sAPPα at concentrations between 0 ng/ml and 50 ng/ml. Results were calculated from the 665 nm/620 nm ratios and expressed in delta F. Slope for r-CSF: 0.83 ± 0.04; slope for recombinant r-sAPPα: 0.76 ± 0.04.

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