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Figure 6 | BMC Neuroscience

Figure 6

From: New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: preclinical and clinical applications in Alzheimer’s disease

Figure 6

Concentrations of different biomarkers in the CSF of two groups of patients previously diagnosed as AD and non-AD. A: 4 μg of CSF proteins were separated in 10% SDS-PAGE for western blotting. h-sAPPα (two isoforms) present in CSF are recognized by both the 6E10 (1) and the 22C11 (2) antibodies. The anti-mouse secondary antibody (3) recognized non specifically some bands. B-E: Concentrations of biomarkers in the CSF of AD patients group were compared to those in the CSF of non-AD patients. **: p < 0.01; ***: p < 0.001.

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