Figure 2
From: Schwann cells migrate along axons in the absence of GDNF signaling
PP2, applied at DIV0, prevents axonal SC colonization. A: Scheme of experimental setup (Expl. = Explantation, Analy. = Analysis, DIV = Day In Vitro). NGF as well as PP2 were added at DIV0 after SCG explantation. B/C: close up of axons grown from SCG explants. Scale bars = 100 μm. Numerous SCs populating axons also in distal regions can be observed in a control explant (B) whereas only bare axons are visible in a PP2 treated explant (C).