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Figure 7 | BMC Neuroscience

Figure 7

From: Cellular elements for seeing in the dark: voltage-dependent conductances in cockroach photoreceptors

Figure 7

Hyperpolarization-activated inward rectifying (IR) current. A) Hyperpolarizing voltage clamps from -74 mV to -124 mV elicited a small-amplitude IR current that activated slowly and showed no inactivation. The sharp transients at the end of the clamp currents are capacitive transients. B) The IR current was insensitive to changes in the external potassium concentration, ruling out potassium as the current carrier. Black circles with [K]o = 5 mM, white squares [K]o = 20 mM (mean ± SEM, n = 4). C) Replacing the NaCl in the bath with Na-gluconate reduced the IR current, indicating that the IR current is carried at least partly by chloride. Black circles are controls with NaCl, white squares are substitution experiments with Na-gluconate (mean ± SEM, n = 4).

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