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Table 2 Anatomical criteria adopted to manually segment ROIs

From: Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington’s disease

Brain regions

Anatomical boundaries for regions of interest (ROIs)

Whole brain

Anterior - the first slide behind the eye sacs

 

Posterior - the first slide where the hemispheres disappear

Lateral ventricle

Hyperintense T2 signal of the cerebrospinal fluid

Striatum

Dorsal - corpus callosum

 

Lateral - external capsule

 

Medial - lateral ventricle

 

Ventral - anterior commissure

Cortex

Internal - corpus callosum & vertical line from lateral edge

 

External - skull

 

Inferior - horizontal line from anterior commissure

Hippocampus

External - corpus callosum

 

Internal - external capsule