Figure 3From: Pheromonal bile acid 3-ketopetromyzonol sulfate primes the neuroendocrine system in sea lampreySex difference in forebrain gene expressions after exposure to synthesized pheromone component in sea lamprey. Exposure to 10-11Â M 3kPZS increased Jun mRNA (2Â h, p < 0.05) but decreased lGnRH-III mRNA concentrations (8Â h, 48Â h, p < 0.05) in the forebrain of immature females (A-C). Exposure to 3kPZS increased GAP49, 50, 58, lGnRH-III, Jun and JNK mRNA concentrations in the forebrain of immature males (D-E). The following data points are statistically different from 0Â h control (p < 0.05). D. GAP49: 8Â h, 24Â h, and 48Â h; GAP58: 4Â h, 8Â h, 24Â h & 48Â h; GAP50: 24Â h; lGnRH-III: 2 4Â h & 48Â h; Jun: 24Â h & 48Â h; JNK: 24Â h & 48Â h. E. GAP49: 8Â h & 24Â h; GAP58: 8Â h & 24Â h; GAP50: 8Â h, 24Â h & 48Â h; lGnRH-III: 8Â h & 24Â h; Jun: 8Â h & 24Â h; JNK: 8Â h & 24Â h. F. GAP49: 4Â h & 48Â h; GAP58: 4Â h; lGnRH-III: 4Â h; Jun: 48Â h.Back to article page