Astroglial immunostaining in the hippocampus of wild-type, E10+/− and E10−/− mice. Coronal sections from 12 months-old mice were stained with a GFAP-antibody. Differences in glial staining were not apparent in E10+/− and E10−/− mice when compared to wild-type (E10+/+) mice. Magnification of CA1 region is marked with arrowheads. Scale bars measure (A-C) 500 μm or (D-F) 125 μm.