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Figure 6 | BMC Neuroscience

Figure 6

From: Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitromodels of the rat blood-brain barrier and blood-spinal cord barrier

Figure 6

Barrier function demonstrated by RSCEC monolayers co-cultured on cell culture inserts with mixed glial cells. Relationship between pre-experimental TEER, measured at room temperature, and permeability to Lucifer yellow over 90 minutes at 37°C in the optimised EBM-2/EGM-2 media conditions. Data was fitted to a one-phase exponential decay curve, R2 = 0.91, n = 8 independent cell culture experiments, 24 cell culture inserts in total.

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