Figure 3From: Enriched environment and masticatory activity rehabilitation recover spatial memory decline in aged miceExperimental timeline. Female albino Swiss mice were housed either in impoverished or enriched environments (middle panel left) from postnatal days 21 until 180 (6 months old; 6M) or 540 (18 months old; 18M), under one of the following diet regimes: HD groups correspond to continuous pellet diets; HD/SD regimes for 6 or 18 months correspond to alternating pellet and powder diet every 3 or 9 months, respectively; HD/SD/HD regimes for 6 or 18 months correspond to sequences of pellet, powder, and pellet food every 2 or 6 months, respectively. All 6M and 18M animals were submitted to the Morris water maze (middle panel, right) between 180 and 195 and between 540 and 555 postnatal days, respectively. Bottom panel: pellet (hard diet) and powder (soft diet) food. Time is represented in days after birth and increases from left to right.Back to article page