Figure 6
Recording site and stimulus point locations and data analysis. A: (a) Recording sites in the PFC. All unit discharges are scattered throughout the cingulate and prelimbic areas. Solid circles represent the recording sites. Drug injection and recording sites (solid triangles: D2R antagonist, solid squares: D1R antagonist, and open triangles: D2R agonist). The numbers represent the distance from the Bregma. Cg1: cingulate cortex area 1. PrL: prelimbic cortex. IL: infralimbic cortex. (b) Stimulus and drug injection sites in the VTA. Solid circles represent the locations to which HFS was delivered. Open circles represent the locations at which the κ-opiate receptor agonist was injected. B: (a) The top trace is multiple unit discharges. The second trace represents discriminated single units. The bottom trace represents a pressure curve. Nociceptive stimulation activated discharges. (b) Cluster analysis of single units (red) with wave width and height on the left. Right side traces represent waves on the left figure. Red units on the left have the same forms. (c) Responses are shown as a histogram with 1sec bin after single units were discriminated. Vertical lines represent the stimulus starting point.