Table 1 Predicted Effectiveness of AED Target
From: Designing anti-epileptic drugs using neuronal dynamics
Parameter (Current) | PRC SSE | Parameter (Current) | PRC SSE | Parameter (Current) | PRC SSE | Parameter (Current) | PRC SSE |
|---|---|---|---|---|---|---|---|
theta nt (KDR) | 10.8 | sigma a (KA) | 39.2 | theta m (Na) | 86.9 | sigma n (KDR) | 106.5 |
theta b (KA) | 21.4 | sigma nt (KDR) | 41.2 | sigma ht (Na) | 90.2 | theta p (NaP)1 | 108.4 |
theta a (KA) | 22.4 | sigma h (Na) | 51.3 | gL (Leak) | 94.7 | theta h (Na)1,3-7 | 115.9 |
gKA (KA) | 26.1 | theta ht (Na) | 54.4 | sigma p (NaP) | 100.0 | theta z (Kslow) | 134.4 |
sigma b (KA) | 28.4 | gKSlow (Kslow) | 74.8 | sigma m (Na) | 101.7 | sigma z (Kslow) | 138.9 |
gKDR (KDR) | 38.1 | gNa (Na) | 82.0 | gNaP (NaP) | 102.7 | theta n (KDR)2 | 156.3 |