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Table 1 Physiological variables

From: Microcirculatory, mitochondrial, and histological changes following cerebral ischemia in swine

 

Group

 

Control (n = 6)

UCO (n = 3)

BCO (n = 4)

BCOH (n = 4)

Body weight (kg)

19.5 ± 2.8

17.3 ± 2.3

22.8 ± 3.3

22.0 ± 3.4

HR (beats/min)

    

Before carotid ligation

125 ± 15

112 ± 11

122 ± 21

112 ± 25

At brain biopsy

111 ± 15

115 ± 9

103 ± 15

138 ± 16ab

MAP (mmHg)

    

Before carotid ligation

101 ± 14

92 ± 4

105 ± 6

99 ± 17

At brain biopsy

94 ± 11

85 ± 9

89 ± 18

42 ± 7ab

Arterial pH (mmHg)

    

Before carotid ligation

7.50 ± 0.01

7.40 ± 0.01

7.53 ± 0.03

7.49 ± 0.06

At brain biopsy

7.49 ± 0.02

7.52 ± 0.02

7.55 ± 0.04

7.39 ± 0.01ab

Arterial pO2 (mmHg)

    

Before carotid ligation

107.2 ± 27.1

116.0 ± 48.1

98.3 ± 30.1

76.8 ± 11.6

At brain biopsy

100.0 ± 15.0

120.0 ± 50.5

82.7 ± 7.3

71.7 ± 9.8

Arterial pCO2 (mmHg)

    

Before carotid ligation

38.8 ± 6.1

38.3 ± 7.6

41.0 ± 6.5

38.1 ± 6.3

At brain biopsy

35.0 ± 8.0

37.0 ± 1.4

36.3 ± 4.6

41.3 ± 7.0

Esophageal temperature (ºC)

    

Before carotid ligation

39.3 ± 1.0

39.5 ± 1.0

38.3 ± 0.6

38.6 ± 0.9

At brain biopsy

39.4 ± 0.9

39.0 ± 1.2

38.0 ± 0.7

37.8 ± 0.7

  1. BCO, bilateral carotid occlusion; BCOH, bilateral carotid occlusion with systemic hypotension; MAP, mean arterial blood pressure; UCO, unilateral carotid occlusion. Values are mean ± SD. ap < 0.05 vs. before carotid ligation; bp < 0.05 vs. control.