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Table 1 Patient characteristics

From: Repeated mapping of cortical language sites by preoperative navigated transcranial magnetic stimulation compared to repeated intraoperative DCS mapping in awake craniotomy

 

Patient 1

Patient 2

Patient 3

1st surgery

2nd surgery

1st surgery

2nd surgery

1st surgery

2nd surgery

Age (years)

47

48

29

30

51

52

Gender

Male

Female

Female

Years of education

10

10

19

Tumor entity

glioblastoma WHO grade IV

glioblastoma WHO grade IV

astrocytoma WHO grade III

astrocytoma WHO grade III

glioblastoma WHO grade IV

glioblastoma WHO grade IV

Tumor location

opIFG

opIFG

anG

anG

opIFG

opIFG

Tumor volume (cm 3 )

20.6

21.7

65.5

6.7

195.4

45.3

Time between surgeries (months)

7

15

10

Adjuvant therapy before surgery

none

RTx & TMZ

none

TMZ

none

RTx & TMZ

Correct baseline pictures (out of 131)

104 (79%)

102 (78%)

101 (77%)

98 (75%)

81 (62%)

98 (75%)

RMT (% output)

30

30

34

35

28

33

Mapping intensity (% of MT)

110

100

100

100

100

100

Most comfortable frequency

5 Hz/5

7 Hz/5

5 Hz/5

5 Hz/5

5 Hz/5

7 Hz/7

Pain during stimulation (VAS): convexity

3

4

2

4

1

7

Pain during stimulation (VAS): temporal

6

7

7

6

4

7

Number of errors left hemisphere

119

62

151

135

151

83

Number of stimulations left hemisphere

750

390

675

405

641

258

Error rate left hemisphere

15.9%

15.9%

22.4%

33.3%

23.6%

32.2%

no response

3.3%

6.2%

13.3%

8.6%

2.8%

8.9%

performance

2.5%

1.3%

2.5%

7.4%

8.6%

9.3%

hesitation

9.7%

7.4%

5.6%

16.0%

9.5%

13.6%

neologism

0.3%

0.0%

0.7%

0.7%

2.7%

0.0%

phonological error

0.0%

0.5%

0.0%

0.0%

0.0%

0.0%

semantic error

0.0%

0.5%

0.1%

0.5%

0.0%

0.4%

Preoperative aphasia

0

0

0

1A

1A

2A

Postoperative aphasia (5th day after surgery)

0

0

1B

1A

2A

2A

Postoperative aphasia (3 months after surgery)

0

0

0

1A

0

2A

Extent of tumor resection

Complete

Complete

Complete

Complete

Complete

Partial

  1. This table shows the characteristics of all patients including pre- and intraoperative findings. Aphasia scale: 0 (no aphasia), 1 (mild aphasia with unremarkable communication), 2 (slightly impaired communication), 3 points (severe grade of aphasia); motoric aphasia = A, sensory aphasia = B. Moreover, the extent of tumor resection is presented. RMT = resting motor threshold (% stimulator output), VAS = visual analogue scale, RTx = radiotherapy, TMZ = Temozolomide.