Gene expression changes in aging Zebrafish (Danio rerio) brains are sexually dimorphic

BMC Neuroscience

Table 1 Gene Ontology comparisons by gender and age

		F vs. M comparison		Y vs. O comparison
Description	GO ID	X	E	X	E
Cellular component	5575	371	74% male	624	72% young
Biological process	8150	337	76% male	560	73% young
Cellular process	9987	176	77% male	336	75% young
Cell differentiation	30154	28	79% male	54	87% young
Regulation of gene expression	10468	31	68% male	49	80% young
Nervous system development	7399	35	83% male	45	86% young
Anatomical structure morphogenesis	9653	37	84% male	59	85% young
Neurogenesis	22008	18	78% male	30	83% young
Generation of neurons	48699	17	76% male	27	81% young
Angiogenesis	1525	10	90% male	12	75% young
Brain development	7420	13	69% male	18	94% young

All of the Gene Ontology Identification Numbers (GO IDs) listed here are significant (p < 0.05) in both young vs. old and female vs. male comparisons. X, Number of significant genes in the list; E, Enrichment.

ISSN: 1471-2202