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Table 3 Median histopathologic scores for the lung and heart tissues from each group

From: Ischemia modified albumin increase indicating cardiac damage after experimental subarachnoid hemorrhage

 

Control group

Day 1 group

Day 2 group

Day 7 group

p value

n = 7

n = 7

n = 7

n = 7

Lung

     

Interstitial edema

0 (0 – 1)

1 (1 – 2)

1 (1 – 2)

2 (2 – 3)

<0,001

Hemorrhage

1 (0 – 1)

2 (2 – 2)

2 (2 – 2)

3 (2 – 3)

<0,001

Epithelial injury

0 (0 – 1)

1 (1 – 2)

1 (1 – 2)

2 (1 – 2)

<0,001

Hyalin membrane formation

0 (0 – 0)

1 (1 – 1)

1 (1 – 2)

2 (1 – 2)

<0,001

Neutrophil infiltration

0 (0 – 1)

2 (1 – 2)

2 (1 – 2)

2 (2 – 3)

<0,001

Emphysematous changes

0 (0 – 1)

1 (1 – 2)

2 (1 – 2)

2 (2 – 3)

<0,001

Lymphocytic infiltration

1 (0 – 1)

1 (1 – 2)

2 (1 – 2)

2 (1 – 2)

0,017

Total injury score

2 (1 – 4)

9 (8 – 13)

11 (9 – 13)

15 (11 – 18)

<0,001

Heart

     

Myocardial edema

0 (0 – 0)

1 (1 – 2)

1 (1 – 2)

2 (2 – 2)

<0,001

Myocytolysis

0 (0 – 1)

1 (1 – 2)

2 (1 – 2)

3 (3 – 3)

<0,001

Focal hemorrhage

0 (0 – 1)

1 (1 – 2)

2 (1 – 2)

3 (3 – 3)

<0,001

Leukocytic infiltration

0 (0 – 0)

1 (0 – 2)

1 (1 – 2)

2 (1 – 2)

<0,001

Loss of cross striation

0 (0 – 0)

1 (1 – 1)

1 (1 – 1)

2 (1 – 2)

<0,001

Total injury score

0 (0 – 2)

5 (4 – 9)

7 (6 – 8)

11 (10 – 12)

<0,001

  1. Median (Min - Max).