Figure 2

Effects of mirtazapine on the striatal dopamine, DOPAC and HVA contents. Values are expressed as means ± SEM, n = 5 mice/group. Mirt.(4), mirtazapine 4 mg/kg; Mirt.(16), mirtazapine 16 mg/kg. Statistical significance was evaluated by one-way ANOVA followed by Student-Newman-Keuls test (F_{(DA) 4,20} = 15.423, F_{(DOPAC) 4,20} = 10.767, F_{(HVA) 4,20} = 6.643, F_{(Turnover) 4,20} = 4.951, *P < 0.05, **P < 0.01 compared with MPTP-treated group) or by Student’s t-test (^##P < 0.01 compared with vehicle group).