From: Proteome analysis reveals roles of L-DOPA in response to oxidative stress in neurons
Spot ID | Protein ID | Description | Mass | PI | Score | Protein coverage | AVG fold change | p-value | q-value | GO (Biological Process) |
---|---|---|---|---|---|---|---|---|---|---|
1 | P07954 | Fumarate hydratase, mitochondrial | 54714 | 8.85 | 408 | 27.2 | 8.27 | 2.10E-03 | 4.68E-04 | GO:0009056 ~ catabolic process, GO:0042592 ~ homeostatic process |
2 | Q16836 | Hydroxyacyl-coenzyme A dehydrogenase | 34613 | 8.76 | 118 | 21.5 | 4.81 | 3.22E-04 | 1.38E-03 | GO:0055114 ~ oxidation reduction |
3 | Q9Y281 | Cofilin-2 | 18764 | 7.66 | 113 | 33.1 | 7.4 | 2.75E-05 | 1.75E-03 | GO:0030042 ~ actin filament depolymerization |
4 | P60981 | Destrin | 18852 | 8.14 | 147 | 26.1 | 5.08 | 1.62E-04 | 1.75E-03 | GO:0006928 ~ cell motion, GO:0043243 ~ positive regulation of protein complex disassembly |
5 | P23528 | Cofilin-1 | 18776 | 8.22 | 192 | 50.6 | 4.1 | 3.15E-03 | 1.99E-03 | GO:0006928 ~ cell motion, GO:0043243 ~ positive regulation of protein complex disassembly |
6 | O00746 | Nucleoside diphosphate kinase | 17469 | 7.77 | 1024 | 41.4 | 2.7 | 3.71E-03 | 2.34E-03 | GO:0009116 ~ nucleoside metabolic process |
7 | Q9BYZ2 | L-lactate dehydrogenase A-like 6B | 36817 | 7.62 | 244 | 29.6 | 4.52 | 1.02E-02 | 4.48E-03 | GO:0055114 ~ oxidation reduction, GO:0006096 ~ glycolysis |
8 | P04083 | Annexin A1 | 38816 | 6.57 | 142 | 6.62 | 1.88 | 3.49E-03 | 4.48E-03 | GO:00070301 ~ cellular response to hydrogen peroxide, GO:0006954 ~ inflammatory response |
9 | Q99497 | Protein DJ-1 | 20064 | 6.33 | 501 | 21.2 | 8.58 | 4.11E-04 | 4.48E-03 | GO:0006979 ~ response to oxidative stress, GO:0042592 ~ homeostatic process |
10 | P30041 | Peroxiredoxin-6 | 25109 | 5.74 | 348 | 35.7 | 12.7 | 5.85E-04 | 5.26E-03 | GO:0009056 ~ catabolic process, GO:0055114 ~ oxidation reduction |
11 | P08670 | Vimentin | 53754 | 5.06 | 1536 | 62.2 | 0.08 | 2.21E-03 | 5.26E-03 | GO:0006928 ~ cell motion |
12 | P67936 | Tropomyosin alpha-4 chain | 28620 | 4.65 | 138 | 23.8 | 0.07 | 2.47E-02 | 5.26E-03 | GO:0006928 ~ cell motion |
13 | P09493 | Tropomyosin alpha-1 chain | 32746 | 4.69 | 405 | 33.1 | 0.12 | 2.37E-03 | 6.41E-03 | GO:0006979 ~ response to oxidative stress, GO:0006928 ~ cell motion, GO:0046907 ~ intracellular transport |
14 | O14556 | Glyceraldehyde-3-phosphate dehydrogenase | 35953 | 8.49 | 1165 | 48.6 | 0.22 | 9.05E-03 | 1.04E-02 | GO:0055114 ~ oxidation reduction, GO:0006096 ~ glycolysis, GO:0006928 ~ cell motion |
15 | Q9UBR2 | Cathepsin Z | 34658 | 6.13 | 308 | 15.7 | 0.18 | 4.90E-03 | 1.04E-02 | GO:0006508 ~ proteolysis |
16 | Q08752 | Peptidyl-prolyl cis-trans isomerase D | 20436 | 6.77 | 139 | 8.88 | 0.12 | 9.20E-03 | 1.08E-02 | GO:0043065 ~ positive regulation of apoptotic process |
17 | Q9Y4L1 | Hypoxia up-regulated protein 1 | 1E + 05 | 5.09 | 192 | 27 | N/A | N/A | N/A | GO:0042221 ~ response to chemical stimulus, GO:0006950 ~ response to stress |
18 | P10809 | 60Â kDa heat shock protein | 61105 | 5.72 | 289 | 29.6 | 4.77 | 8.26E-04 | 2.47E-02 | GO:0032943 ~ mononuclear cell proliferation |