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Phase lead/lag due to degree inhomogeneity in complex oscillator network with application to brain networks

Brain anatomical connectivity is one of the main factors influencing information flow among the brain areas [1] and phase lead/lag relationship between oscillations of brain areas is known to be related to the information flow [2, 3]. In this study, we analyze the network effect on the phases of coupled oscillators using Kuramoto model and obtain analytical relationship between phase lead/lag and degrees of network nodes. We also show robustness under various conditions, improving upon the result of ref. [4]. Using the brain anatomical connectivity and the relationship, we can explain the phase distribution across the brain. At first, we investigate the relationship in the oscillator model on a scale-free network of which degree distribution follows a power law [5]. Confirming the result of previous study [4], the phases of higher degree nodes lag the phases of lower degree nodes. Similar behaviors are observed also in random network, where the degree distribution follows a Poisson distribution. Using mean-field approximation, we analytically derive the relationship between phases and node degrees as shown in Figure 1. With various conditions of time delay and coupling strength, we also observe that this phase lead/lag relationship between nodes is robust. Our exact relationship can be well applied to human brain anatomical networks.

Figure 1
figure1

The phase (black dots) of each oscillator and the calculated phases (red line) from analytic derivation. They match well in locked region and red shaded area represents drifting region. The inset shows the degree for each node.

References

  1. 1.

    Stam CJ, van Straaten EC: Go with the flow: use of a directed phase lag index (dPLI) to characterize patterns of phase relations in a large-scale model of brain dynamics. Neuroimage. 2012, 62: 1415-1428.

    PubMed  CAS  Article  Google Scholar 

  2. 2.

    Rabinovich MI, Afraimovich VS, Bick C, Varona P: Information flow dynamics in the brain. Phys Life Rev. 2012, 9: 51-73.

    PubMed  Article  Google Scholar 

  3. 3.

    Akam T, Kullmann DM: Oscillatory multiplexing of population codes for selective communication in the mammalian brain. Nat Rev Neurosci. 2014, 15: 111-122.

    PubMed  CAS  Article  Google Scholar 

  4. 4.

    Moon J-Y, Lee UC, Blain-Moraes S, Mashour GA: General relationship of global topology, local dynamics, and information flow in simulated and empirical brain networks. PLOS Comp Biol. 2015, (to be published)

    Google Scholar 

  5. 5.

    Ko T-W, Ermentrout GB: Partially locked states in coupled oscillators due to inhomogeneous coupling. Phys Rev E. 2008, 78: 016203-

    Article  Google Scholar 

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Correspondence to Tae-Wook Ko.

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Kim, J., Moon, JY., Lee, U. et al. Phase lead/lag due to degree inhomogeneity in complex oscillator network with application to brain networks. BMC Neurosci 16, P127 (2015). https://0-doi-org.brum.beds.ac.uk/10.1186/1471-2202-16-S1-P127

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Keywords

  • Coupling Strength
  • Information Flow
  • Degree Distribution
  • Network Node
  • Random Network